Endocrine Abstracts

The article is devoted to one of the most pressing medical problems – diabetes mellitus type 2.Objective: To study the peculiarities of the course of diabetes mellitus type 2 in persons over 65 years of age; to evaluate the effectiveness of different therapy regimens for the level of HbA1C.Material and methods: The retrospective study included 100 patients with type 2 diabetes (T2D). The age of the patients: 65 to 82 years. Th...

One of the most frequent complications of diabetes is diabetic sensorimotor peripheral polyneuropathy (DSPN). B vitamins successfully used for the treatment DSPN. However, prolonged use of vitamins B6 and B12 in effective doses limited by the comorbidities and possibility of the neurotoxic reactions development, as for vitamin B1, its low bioavailability of water-soluble forms. This determines whether the use of fat-soluble form of benfotiamine with maximum bioavailability.</p...

Recently we described clinical case of 38-year-old fertile woman with sudden onset of a multiple clinical symptoms: weight gain, secondary amenorrhea, hirsutism and seizures. Adrenal tumour co-secreted high amounts of DHEA sulfate, testosterone (T) and aldosterone (A) (Matulevicius et al. 2014). The symptoms of the disease disappeared after laparoscopic removal of adrenal tumour, which proved to be an adrenocortical oncocytoma. A hypersecretion of A remained after res...

Screening for diabetic polyneuropathy (DP) is advisable for all patients with type 1 diabetes mellitus (T1DM) after 5 years the detection of the disease. The aim of the study was to evaluate the vibration sensitivity disorders in T1DM patients using Vibratip device for early diagnosis of DP.Materials and methods: 509 patients with T1DM (224 women and 285 men) (mean age: 28.5±8.5 years, mean BMI −24.2±4.1 kg/m2) were examined. T...

Background and aim: Hypersomatotropism is known to be associated with musculoskeletal disorders, particularly, osteoporosis and increased fracture rates. However controversial data about the effects of acromegaly on bone mineral density (BMD) have been published. The aim of our research was to evaluate bone mineral density (BMD) in patients with hypersomatotropism.Materials and methods: The study included 66 patients (20 men, 44 women) with hypersomatotr...

Introduction: Primary hyperparathyroidism (PHPT) is a result of overproduction of parathyroid hormone with pathologically changed parathyroid glands (PTG) and calcium-phosphorus metabolism disorders. Until now, PHPT is often detected late (in countries where there is no screening for hypercalcemia), when there are irreversible complications it manifested.Materials and methods: One hundred and nine patients with PHPT (mean age: 52.2±8.7 year...

The rapidly increasing epidemic of obesity is one of the most challenging dilemmas facing endocrinologists all over the world today. The aim of our research was within the framework of the National Campaign ‘Early Detection and Prevention of Type 2 Diabetes Mellitus’ to evaluate the prevalence of obesity and overweight in the Belarusian population.Materials and methods: The Campaign involved opportunistic screening of individuals applying to th...